Free Radicals Mediate Cardiac Toxicity Induced by Adriamycin
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چکیده
منابع مشابه
Mn Superoxide Dismutase and Adriamycin-induced Cardiac Toxicity
Adriamycin (ADR) is a potent anticancer drug known to cause severe cardiac toxicity. Although ADR generates free radicals, the role of free radicals in the development of cardiac toxicity and the intracellular target for ADR-induced cardiac toxicity are still not well understood. We produced three transgenic mice lines expressing increased levels of human manganese superoxide dismutase (MnSOD),...
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Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40536, USA Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand Department of Chemistry, Center of Membrane Sciences, and Sanders-Brown Center on Aging, 121 Chemistry-Physics Building, University of Kentucky, Lexington, KY 40506, USA Department of Physiology, University of Kentucky, Lexington, KY 40536, USA D...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2003
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.123.855